MS Monitor 1206

R esponse to our first issue of Multiple Sclerosis Monitor and Commentary was excellent. The consensus was that we fulfilled our goal of placing recently published articles about the pathogenesis and care of multiple sclerosis (MS) into context. This, the second issue, has the same intent. By matching experts with topics in which they have experience, we have an opportunity to go beyond the restraints of published manuscripts to consider what relevance, if any, new information may have to our understanding of MS and its care. In this issue, the topics addressed are as intriguing as in our inaugural issue. These include whether systemic infections increase the risk of MS relapses, whether cholinesterase inhibitors may have a role in preventing cognitive loss in MS, and what role high-dose cyclophosphamide may have in the control of moderate to severe MS. Of less immediate importance to clinical management but no less intriguing, the phenomenon of remyelination in MS and the correlation between plaque load and axonal loss are examined. Keeping current with the medical literature is an increasingly daunting task. We hope this publication can facilitate the process by not only summarizing recent information but providing expert commentary on its relevance and importance. Comments are welcome. We have added two new ways to communicate with us. First, please feel free to email us at [email protected]. We would like to hear your comments on some of the articles we addressed as well as your thoughts on the publication. Or, on page 11, please take a moment to fill out the issue evaluation form and fax it back to us at 201-612-8282. We look forward to hearing from you and sharing your comments with readers in the next issue.